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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c511b5ce678c6eef18a8a578d36d7571654f75ae5a2b2f9c5236b315320b18' 
  AND token = 'gFWIfC5z7uYXM5548bNKnmt0aX8/5APIbjGXTgetD0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}