SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb91b75fbb4b9e4ed0a4b0a43afe75253c2f1e64bb0ec69db8386df26616f55' 
  AND token = 'YW4LM49HRdW7nTyHqVRQKel87tw+vf9Z5TNqRhwPZeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}