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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bb33b0b150fd4b2b6e7298f135d1d1625111a653daa29ed41271b1057c61bbc' 
  AND token = 'gh7hBKtnKVvZsHjE7sznnMUiTzg8WXSHPZ/Wo6y1BDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}