SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e01314c540666f5101482246066728d47aa9e3e98077e295af0a04d60466099' 
  AND token = 'LwEI6fvVxOoUiSKjTRO63pDLB1aXluYMlr0KIygalCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}