SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88faa41096270c8325ece94fcdbbdd7b74921feb0af36ab97c3ba2f3c39f4f82' 
  AND token = 'iu/PyDiIcYKOb9VuSK3+kgwvCMYVaeqMfyqUt9VAp3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}