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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cca367dd766cb2e80cc6b6182d9d04597a1fe1be8827ff68631cc197c09340' 
  AND token = '+onWhz3WwLavS1SBTxT0I3vcFN/GI38xVl+f7GIXHv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}