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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4169686999524e90e63c3f4dcade8d976414337ac3f18bf54b5f032a1f96f0ec' 
  AND token = 'LtFRhKv+G6Q0UH/sc1W1na+3J12ZG84nv6Nrzx3UFkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}