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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '713b81c34f7479502df5f2e0258f59c4dc7d57c6247ddedea44b32324e838261' 
  AND token = 'j7Ri0CCGPMYuEaey3+q0fM9tRcwXwtc91oqpkSGS4Ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}