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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb16a05e9fa4b05be7dc424049be467eb1253c4995004f155b5153ae0bf7fe59' 
  AND token = 'PtdqCyP9TTquGqa9KaLAQfrPO5/YrsFmaCd+EJ3U3ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}