SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44fadbb6092a0241e8fd5cc34deb3bc5d232288aded6e3b9dc08d26451bfb0a' 
  AND token = 'I2ukDq4ZaO7IibZxjP0DOj/weUlGyfxsIRKMuM0GHsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}