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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961166c32a8e54753c1b9e7a1a6feaacf58859abe0e46679d5b39f749bb7c19d' 
  AND token = 'MUq6tjKVvvfdFOmRn8cwldor4+uEoo+5T6vjhhTRZ/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}