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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa8bb21864344bb0927905861a34a3ffb0503ca43117a022a35eeeaa82427ee0' 
  AND token = 'E+uIkkawvWewvG/XCoJw5J2W7OKtnnkYGN4Yy5uJMpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}