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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c54aa28d3256f194f3a890ada327584e30c42508e189b4a16c8060990f01ec3d' 
  AND token = 'ZlRyt3nYZdsVT2uptPesMGb+Zvx5XTk+B5OzXliEW9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}