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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9937b29064898cfb54e1b50d3a56a8cc1bc675dc74835eac41956470aec489' 
  AND token = '8c2A02aFe9+lK+gg6VZ9+EX0Kwpc0rrIvRCjFF+6wxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}