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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d304f4b7cc7dc7b835dd7d6409c756b8f808595ce58b065f77401bc9afafce' 
  AND token = 'esEhtAGLcCaCYwcX1ZBSnIhhWkMpYEo4hIrLYNeff0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}