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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8228313118efde8dd2a0060fcdff004007e97ac97cf227af5ff866d62916b9' 
  AND token = 'qFYDgPnLHNod+sK3dcjhBtjohsOQ0aB4sRJlKv+Q77Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}