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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18468a7177a8a63f8fe9a1eea17aacef6f98e4fc7326f1844be31f355cb5d433' 
  AND token = '4PHgVj6ulqieSGnKWDhQWlddIHDnFtGERCb5Dq6QKA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}