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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afc4654296b6622ee61aaf44a420757c6dd510ff479be3aa4d7696687f4afe7' 
  AND token = 'CJpv82mT76h/xyTp65Ic76DoLM07MWi1a/MiZuWa8E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}