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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efdb350486345ebef3cf68ed966289fef5ca45b8ffa81c967b0bc2d8449b6660' 
  AND token = 'irRSI/vmAnyYDS6iSUJIc5wpJySy/2zfwSwlgVHSSLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}