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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d0d072363a3c25b306a2fa20dac5e61ff50de795e20b0cec8f1607e83bdd83b' 
  AND token = 'aOUbEIWDAzWt0+DI4idSEBMZldv51thj2QjnaXGvJVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}