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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c28a8c6c83e6b3fe8083eb830a52fe76aaf5cd8a3450d886f68cc73c156c273' 
  AND token = 'HlGWJqxmEqNiFcOUiHo43537SFyncaTkfJ5iGVqZZUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}