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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e28e63f829cf89aa44d20bcd8a57be12e3235e736fc3775860742958599cd59' 
  AND token = 'cZcZN4A32QRC1CdY4+bTMPZ9hQdsUxA5LMe7OzbwA7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}