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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfde6c09413ffa41215d0ed97c8a70bdbdab16e83d8e0dc6c426b99144afd7e9' 
  AND token = '4lU00JLgOlh+XcdR7s2wDpZnISHwHdCgwUu2h9cTAWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}