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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f75eaa6bd48644237394525e835b3752bf20ae889d3a3966b9d11e206e1a928a' 
  AND token = '48H6pBe1CZCFF/567L/MxLajWAtxO7RWxplQJkvkZmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}