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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ecaddab5cb7174340f0e6d7107c311b48f185d6b7a4f5318a6bcc5fac080e69' 
  AND token = 'plV79dc2sTdaIRVK+pEUFutLne2QDnAGmTpk3v4jaQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}