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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780c4b618f253190a7acfec34f67a3aacff3412477a15a9f57f154d2daf704ca' 
  AND token = '5h/wJA4jdnmcNeqUbUUnR2q/c/P8TXilHgNQlQLup0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}