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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cba9878ae3f6e82174f5a88c68aa0448bd0070f693b2c600d1fa96c9931f8fb' 
  AND token = 'LCEkoyIGaNNVVRdp++3oChvTnXWkme3joRg2AbPndzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}