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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9b4e283b70185b39358fe242b616e86f1ea013d749f3d40aff9dd6fa539114' 
  AND token = 'OrDoZxzJdfX/icqeuxPaMurpglVekm2DQaU7JfpqbxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}