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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3193d648ff16fab48a6966ec2e011ec2a2cb3cc4f48ac0f2d13c2453f78a3e50' 
  AND token = 'I6WwYg+1Q7Cq3cMUv5PSpCbLm7no0YXXIpeV83GAcPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}