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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e940346e244c08bf739e15d9458c2c3589d5619bbcd82cfd34c70b0d8b7c6528' 
  AND token = 'VqayFHfSA1Hs1fGAfLGREy5LdxPDNuwkYSq3/Qs9UPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}