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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1378af183ca9fe6826d9939e117e8c2f9080a82fb0f5444d14af8739be11e9df' 
  AND token = '2XxbJjrgsoG4rK8Q1bR+ZZjfbz7u3AZStdPjRcg7eCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}