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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0a438122eddbe08c46e16f40a1b6226f84a2eb21c72958067d9e6c51d95083' 
  AND token = 'X0VjrmM04jOZq9fAfFbcY+hW3cGMxBeXCTP6tve0bqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}