SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19d285f3bba8933cdb3ae62539c4d22aca7cf3b87cbb37809c4262fb86482ca' 
  AND token = 'zyqPlf7hr8uKj0paaTNmXSrobVq6w9nHqMjXVkaGvBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}