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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c569bd865b95e319101d09108eed5e661862f116c4bffa0dd0114af4e65aae' 
  AND token = 'Kspb+VHKwV5/Ytw/nA0VxMJwEBAVDWy3pM4sqeLqQrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}