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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6fc5407606424e1d9675659becc77a72c4efd81f60014059e8ddf0557899266' 
  AND token = '3JVgrSVhlAK1Bo9f2V5x/H7ZoEb6aRVlOl2CU+H6qOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}