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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dacdd8e654b2aea2ecf1726dc42bb160abdbf5625e6b63117a2c00d8d61c1771' 
  AND token = 'x5/raATaXZ2pz6zeYyjLOrFF6UBJiGlvtTE5zUqaDxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}