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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f66ce28362b367ff84fad00cf3e35579bf31f5e8b9c6fc51898490f965ad7e5' 
  AND token = '9STVUx0+LXrt++ZtBlHYcSZLcTsy2PZ464OZbnEafmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}