SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ec122ff97ae04978a995071cfa6ff23898a21b4f7cbe6c490405531af9b5ec9' 
  AND token = 'lCrHE2mZj8AqMDDVc4vSb5ne88k8oOW7ZHndtt1VSZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}