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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dcec2af2afdc3935a6494281891f59686b1146e8811cc4cc194b76aa2a03f86' 
  AND token = 'XnVv0+XHAUbI2QSplDEIKpg1t1zY4g3fXOgGjQrHu1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}