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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f48d3a748b1f44deb36a70dca1cfce7eaffcf9043b1f64faa3636efaa0d11f' 
  AND token = 'oKeqZ+v+8d7xXEMCAGnDC5jYDeH1Zp8MhsX/FpHMBz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}