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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446873ba45cb96a9702f474247ef571da32695e97a8e4fddf53f4459481e352e' 
  AND token = '9AEbEjuCpgrIzTcRn7rm71++DPxujHcIEHil4ICQ/0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}