SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48e12f48ae1c8100060c796bfa8f5fa774d1da64dadbb6528a573181d96f3cb' 
  AND token = 'qnE9lILG8jZm3Qem9uQkdqY3WawEsPrGme1a5HbwSBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}