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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8dd4176c90f89158943fa2888148351ab53aecc59af0318b3e4bfa0e4dbbec0' 
  AND token = '7/vufvyBU72AcEnHpMNNVsUNPM99YtLx/v/Rp3KQjRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}