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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54188873d4b0ee2895662508fd57cbf9c9daa99318e34cc42d31df3c763efad8' 
  AND token = 'X58yXTCvOkNVTCQsO9CpR5j7UnRUDYdjUQbz2w7ckL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}