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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6fd8d48bd7d75f63c9b3fbe2b19df6da156e29517ea487e467ff4014e10db2f' 
  AND token = 'FskYDUiP6oEdVQE9YN8LVvYw3YPY7YpVf2l06nfS2e4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}