SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dbde64ea479239024ed3315eb64604321ea965d00f9ffc551ddeb96ff02227a' 
  AND token = 'gFe8fJE8ICfF1E7h+WrG3+hBM6/vUqbl5xdqhOvVuv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}