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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8b3ba76bb939092454eaba0de1bdec01442477fe2b42fbad4b51385e164ac9' 
  AND token = 'B5eBBXLGyJeau3/jEzjPhxadb6PBNMmxlmqSfM/wTTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}