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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e037140fd841741647a4467176932b431042541a69ae4996a0e8b897add874' 
  AND token = 'pE4FdFARrV9pC5sSply7FdrSEfIL80m5RXGhw+Y85Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}