SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc3f7aa52b2730bb8ae1e41420b7f196e8c2560289c49a7d4f863a4c8b270fff' 
  AND token = 'THzkFDLVO1NwHKZA9muO4imjEDMQIdnB7aOYdbcmFXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}