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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4433bc9b9468b08fd20b0a45b0ff435273fcf12d8fd5b3d8802245dc2afb8297' 
  AND token = 'YajiCjP84cnlPx8p0oa5iHc8ek8+ND6xRVCs1C/B3BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}